SyrSpend® SF is a unique ready-to-use suspending vehicle that has been gaining momentum in compounding pharmacies worldwide. As an alcohol- and sorbitol-free suspending agent, SyrSpend® SF is safe for vulnerable patients while it also helps mask unpleasant taste, increasing patient compliance. In the March/April issue of the International Journal of Pharmaceutical Compounding (IJPC), SyrSpend® SF’s broad compatibility is further explored and 10 additional stability studies have been performed:
- Diclofenac sodium
- Enalapril maleate
All APIs reached beyond-use dates of at least 90 days when stored at controlled refrigerated (2°C - 8°C) and at controlled room temperature (20°C - 25°C) conditions, except for atenolol 1 mg/mL, which was stable for up to 60 days. This shows that SyrSpend® SF is an appropriate suspending vehicle for the preparation of individualized compounded oral suspensions with these APIs.
An overview of all available formulations with SyrSpend® SF can be found in our free online formulations database, Compounding Matters.
 Polonini HC, Loures S, Lima LC, Ferreira AO, Brandão MA. Stability of Atenolol, Clonazepam, Dexamethasone, Diclofenac Sodium, Diltiazem, Enalapril Maleate, Ketoprofen, Lamotrigine, Penicillamine-D and Thiamine in SyrSpend SF PH4 Oral Suspensions. International Journal of Pharmaceutical Compounding Volume 20 No. 2, March/April 2016.